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The Interface between Extracellular and Transmembrane Domains of Homomeric Cys-Loop Receptors Governs Open-Channel Lifetime and Rate of Desensitization
The lifetimes of activated postsynaptic receptor channels contribute to the efficiency of synaptic transmission. Here we show that structural differences within the interface dividing extracellular and transmembrane domains of homomeric α7 and 5-HT(3A) receptors account for the large differences in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844810/ https://ncbi.nlm.nih.gov/pubmed/18667613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0448-08.2008 |
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