Chargement en cours...

The Interface between Extracellular and Transmembrane Domains of Homomeric Cys-Loop Receptors Governs Open-Channel Lifetime and Rate of Desensitization

The lifetimes of activated postsynaptic receptor channels contribute to the efficiency of synaptic transmission. Here we show that structural differences within the interface dividing extracellular and transmembrane domains of homomeric α7 and 5-HT(3A) receptors account for the large differences in...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bouzat, Cecilia, Bartos, Mariana, Corradi, Jeremías, Sine, Steven M.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844810/
https://ncbi.nlm.nih.gov/pubmed/18667613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0448-08.2008
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!