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Identification and Validation of an Anthracycline/Cyclophosphamide–Based Chemotherapy Response Assay in Breast Cancer

BACKGROUND: There is no method routinely used to predict response to anthracycline and cyclophosphamide–based chemotherapy in the clinic; therefore patients often receive treatment for breast cancer with no benefit. Loss of the Fanconi anemia/BRCA (FA/BRCA) DNA damage response (DDR) pathway occurs i...

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Detalhes bibliográficos
Main Authors: Mulligan, Jude M., Hill, Laura A., Deharo, Steve, Irwin, Gareth, Boyle, David, Keating, Katherine E., Raji, Olaide Y., McDyer, Fionnuala A., O’Brien, Eamonn, Bylesjo, Max, Quinn, Jennifer E., Lindor, Noralane M., Mullan, Paul B., James, Colin R., Walker, Steven M., Kerr, Peter, James, Jacqueline, Davison, Timothy S., Proutski, Vitali, Salto-Tellez, Manuel, Johnston, Patrick G., Couch, Fergus J., Paul Harkin, D., Kennedy, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906990/
https://ncbi.nlm.nih.gov/pubmed/24402422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt335
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