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Mutation screening of RAD51C in high-risk breast and ovarian cancer families
Deleterious mutations in the RAD51C gene, which encodes a DNA double-strand break (DSB) repair protein, have been reported to confer high-penetrance susceptibility to both breast and ovarian cancer. To confirm this we conducted a mutation screen of the RAD51C gene in 192 probands from high-risk brea...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418444/ https://ncbi.nlm.nih.gov/pubmed/22476429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-012-9523-9 |
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