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RAD51C Germline Mutations in Breast and Ovarian Cancer Cases from High-Risk Families

BRCA1 and BRCA2 are the most well-known breast cancer susceptibility genes. Additional genes involved in DNA repair have been identified as predisposing to breast cancer. One such gene, RAD51C, is essential for homologous recombination repair. Several likely pathogenic RAD51C mutations have been ide...

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Bibliografische gegevens
Hoofdauteurs: Clague, Jessica, Wilhoite, Greg, Adamson, Aaron, Bailis, Adam, Weitzel, Jeffrey N., Neuhausen, Susan L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182241/
https://ncbi.nlm.nih.gov/pubmed/21980511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025632
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