Identification and Validation of an Anthracycline/Cyclophosphamide–Based Chemotherapy Response Assay in Breast Cancer

BACKGROUND: There is no method routinely used to predict response to anthracycline and cyclophosphamide–based chemotherapy in the clinic; therefore patients often receive treatment for breast cancer with no benefit. Loss of the Fanconi anemia/BRCA (FA/BRCA) DNA damage response (DDR) pathway occurs i...

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Main Authors: Mulligan, Jude M., Hill, Laura A., Deharo, Steve, Irwin, Gareth, Boyle, David, Keating, Katherine E., Raji, Olaide Y., McDyer, Fionnuala A., O’Brien, Eamonn, Bylesjo, Max, Quinn, Jennifer E., Lindor, Noralane M., Mullan, Paul B., James, Colin R., Walker, Steven M., Kerr, Peter, James, Jacqueline, Davison, Timothy S., Proutski, Vitali, Salto-Tellez, Manuel, Johnston, Patrick G., Couch, Fergus J., Paul Harkin, D., Kennedy, Richard D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2014
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906990/
https://ncbi.nlm.nih.gov/pubmed/24402422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt335
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