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Antibiotic-free production of a herpes simplex virus 2 DNA vaccine in a high yield cGMP process
Two DNA vaccine plasmids encoding Herpes simplex virus type 2 (HSV-2) glycoprotein D, NTC8485-O2-gD2 and NTC8485-O2-UgD2tr, were produced at large scale under current good manufacturing practice (cGMP) for use in a Phase I human clinical trial. These DNA vaccines incorporate the regulatory agency co...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906406/ https://ncbi.nlm.nih.gov/pubmed/23899469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25048 |
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