Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques

A panel of SIVmac251 transmitted Env sequences were tested for expression, function and immunogenicity in mice and macaques. The immunogenicity of a DNA vaccine cocktail expressing SIVmac239 and three transmitted SIVmac251 Env sequences was evaluated upon intradermal or intramuscular injection follo...

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Autori principali: Kulkarni, Viraj, Rosati, Margherita, Bear, Jenifer, Pilkington, Guy R, Jalah, Rashmi, Bergamaschi, Cristina, Singh, Ashish K, Alicea, Candido, Chowdhury, Bhabadeb, Zhang, Gen-Mu, Kim, Eun-Young, Wolinsky, Steven M, Huang, Wensheng, Guan, Yongjun, LaBranche, Celia, Montefiori, David C, Broderick, Kate E, Sardesai, Niranjan Y, Valentin, Antonio, Felber, Barbara K, Pavlakis, George N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906392/
https://ncbi.nlm.nih.gov/pubmed/23811579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25473
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