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Highly efficient selection of epitope specific antibody through competitive yeast display library sorting

Combinatory antibody library display technologies have been invented and successfully implemented for the selection and engineering of therapeutic antibodies. Precise targeting of important epitopes on the protein of interest is essential for such isolated antibodies to serve as effective modulators...

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Main Authors: Puri, Vinita, Streaker, Emily, Prabakaran, Ponraj, Zhu, Zhongyu, Dimitrov, Dimiter S.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906307/
https://ncbi.nlm.nih.gov/pubmed/23765162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.25211
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