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Characterization of human IgG repertoires in an acute HIV-1 infection
All known broadly neutralizing antibodies (bnAbs) are highly somatically mutated and therefore significantly differ from their germline predecessors. Thus although the mature bnAbs bind to conserved epitopes of the HIV-1 envelope glycoprotein (Env) with high affinity their germline predecessors do n...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663482/ https://ncbi.nlm.nih.gov/pubmed/23036472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.09.022 |
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