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454 antibody sequencing - error characterization and correction

BACKGROUND: 454 sequencing is currently the method of choice for sequencing of antibody repertoires and libraries containing large numbers (10(6 )to 10(12)) of different molecules with similar frameworks and variable regions which poses significant challenges for identifying sequencing errors. Ident...

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Detalhes bibliográficos
Main Authors: Prabakaran, Ponraj, Streaker, Emily, Chen, Weizao, Dimitrov, Dimiter S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228814/
https://ncbi.nlm.nih.gov/pubmed/21992227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-404
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