Characterization of human IgG repertoires in an acute HIV-1 infection

All known broadly neutralizing antibodies (bnAbs) are highly somatically mutated and therefore significantly differ from their germline predecessors. Thus although the mature bnAbs bind to conserved epitopes of the HIV-1 envelope glycoprotein (Env) with high affinity their germline predecessors do n...

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Bibliographic Details
Main Authors: Chen, Weizao, Prabakaran, Ponraj, Zhu, Zhongyu, Feng, Yang, Streaker, Emily D., Dimitrov, Dimiter S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663482/
https://ncbi.nlm.nih.gov/pubmed/23036472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.09.022
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