Urine MicroRNA as Potential Biomarkers of Autosomal Dominant Polycystic Kidney Disease Progression: Description of miRNA Profiles at Baseline

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is clinically heterogenic. Biomarkers are needed to predict prognosis and guide management. We aimed to profile microRNA (miRNA) in ADPKD to gain molecular insight and evaluate biomarker potential. METHODS: Small-RNA libraries were gen...

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Hauptverfasser: Ben-Dov, Iddo Z., Tan, Ying-Cai, Morozov, Pavel, Wilson, Patricia D., Rennert, Hanna, Blumenfeld, Jon D., Tuschl, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906110/
https://ncbi.nlm.nih.gov/pubmed/24489795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086856
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