Urine MicroRNA as Potential Biomarkers of Autosomal Dominant Polycystic Kidney Disease Progression: Description of miRNA Profiles at Baseline

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is clinically heterogenic. Biomarkers are needed to predict prognosis and guide management. We aimed to profile microRNA (miRNA) in ADPKD to gain molecular insight and evaluate biomarker potential. METHODS: Small-RNA libraries were gen...

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Hlavní autoři: Ben-Dov, Iddo Z., Tan, Ying-Cai, Morozov, Pavel, Wilson, Patricia D., Rennert, Hanna, Blumenfeld, Jon D., Tuschl, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906110/
https://ncbi.nlm.nih.gov/pubmed/24489795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086856
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