Urine MicroRNA as Potential Biomarkers of Autosomal Dominant Polycystic Kidney Disease Progression: Description of miRNA Profiles at Baseline

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is clinically heterogenic. Biomarkers are needed to predict prognosis and guide management. We aimed to profile microRNA (miRNA) in ADPKD to gain molecular insight and evaluate biomarker potential. METHODS: Small-RNA libraries were gen...

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Detalhes bibliográficos
Main Authors: Ben-Dov, Iddo Z., Tan, Ying-Cai, Morozov, Pavel, Wilson, Patricia D., Rennert, Hanna, Blumenfeld, Jon D., Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906110/
https://ncbi.nlm.nih.gov/pubmed/24489795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086856
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