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HtrA Serine Proteases as Potential Therapeutic Targets in Cancer

The human HtrA family of serine proteases consists of four members: HtrA1, HtrA2, HtrA3 and HtrA4. Although prokaryotic HtrA proteins are well characterized in their dual roles as chaperones and proteases that degrade misfolded proteins in the periplasm, some members of mammalian HtrA proteins are d...

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Bibliografische gegevens
Hoofdauteurs: Chien, Jeremy, Campioni, Mara, Shridhar, Viji, Baldi, Alfonso
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905973/
https://ncbi.nlm.nih.gov/pubmed/19519315
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