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Selective activation of PKC epsilon in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice

Activation of PKCε confers protection against neuronal ischemia/reperfusion. Since activation of PKCε leads to its translocation to multiple intracellular sites, a mitochondrial-selective PKCε activator was used to test the importance of mitochondrial activation to the neuroprotective effect of PKCε...

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Detalhes bibliográficos
Main Authors: Sun, Xiaoyun, Budas, Grant R., Xu, Lijun, Barreto, George E., Mochly-Rosen, Daria, Giffard, Rona
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905808/
https://ncbi.nlm.nih.gov/pubmed/23426889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23186
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