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Inflammatory Dilated Cardiomyopathy in Abcg5 Deficient Mice

Dilated cardiomyopathy (DCM) in A/J mice homozygous for the spontaneous thrombocytopenia and cardiomyopathy (trac) mutation results from a single base pair change in the Abcg5 gene. A similar mutation in humans causes sitosterolemia with high plant sterol levels, hypercholesterolemia, and early onse...

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Detalhes bibliográficos
Main Authors: Wilson, Dennis W., Oslund, Karen L., Lyons, Bonnie, Foreman, Oded, Burzenski, Lisa, Svenson, Karen L., Chase, Thomas H., Shultz, Leonard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905339/
https://ncbi.nlm.nih.gov/pubmed/23129576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623312466191
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