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Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease
OBJECTIVE: Gain-of-function (GOF) mutations in RHBDF2 cause tylosis. Patients present with hyperproliferative skin, and keratinocytes from tylosis patients’ skin show an enhanced wound-healing phenotype. The curly bare mouse model of tylosis, carrying a GOF mutation in the Rhbdf2 gene (Rhbdf2 (cub))...
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| Publicado no: | BMC Res Notes |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678570/ https://ncbi.nlm.nih.gov/pubmed/29116018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2899-8 |
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