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Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY()
The major facilitator superfamily (MFS) transporter lactose permease (LacY) alternates between cytoplasmic and periplasmic open conformations to co-transport a sugar molecule together with a proton across the plasma membrane. Indirect experimental evidence suggested the existence of an occluded tran...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905165/ https://ncbi.nlm.nih.gov/pubmed/24513108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.10.024 |
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