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Apo-intermediate in the transport cycle of lactose permease (LacY)
The lactose permease (LacY) catalyzes coupled stoichiometric symport of a galactoside and an H(+). Crystal structures reveal 12, mostly irregular, transmembrane α-helices surrounding a cavity with sugar- and H(+)- binding sites at the apex, which is accessible from the cytoplasm and sealed on the pe...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497813/ https://ncbi.nlm.nih.gov/pubmed/23012238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211183109 |
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