Rapamycin induces pluripotent genes associated with avoidance of replicative senescence

Primary rodent cells undergo replicative senescence, independent from telomere shortening. We have recently shown that treatment with rapamycin during passages 3–7 suppressed replicative senescence in rat embryonic fibroblasts (REFs), which otherwise occurred by 10–14 passages. Here, we further inve...

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Detaylı Bibliyografya
Asıl Yazarlar: Pospelova, Tatiana V, Bykova, Tatiana V, Zubova, Svetlana G, Katolikova, Natalia V, Yartzeva, Natalia M, Pospelov, Valery A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905076/
https://ncbi.nlm.nih.gov/pubmed/24296616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27396
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