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Latest progress in tyrosine kinase inhibitors

Here we discuss the latest progress in development of some kinase inhibitors such as inhibitors of c-MET, LIM and Bcr-Abl kinases. Importantly, many oncogenic kinases signal via the mTOR pathway, suggesting a common target for drug combinations.

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Detalhes bibliográficos
Main Authors: Pospelova, Tatiana V., Pospelov, Valery A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012733/
https://ncbi.nlm.nih.gov/pubmed/24727648
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