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Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence

BACKGROUND: In culturing normal diploid cells, senescence may either happen naturally, in the form of replicative senescence, or it may be a consequence of external challenges such as oxidative stress. Here we present a comparative analysis aimed at reconstruction of molecular cascades specific for...

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Pubblicato in:BMC Genomics
Autori principali: Kural, Kamil C., Tandon, Neetu, Skoblov, Mikhail, Kel-Margoulis, Olga V., Baranova, Ancha V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249001/
https://ncbi.nlm.nih.gov/pubmed/28105936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3352-4
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