Monitoring Repair of UV-Induced 6-4-Photoproducts with a Purified DDB2 Protein Complex

Because cells are constantly subjected to DNA damaging insults, DNA repair pathways are critical for genome integrity [1]. DNA damage recognition protein complexes (DRCs) recognize DNA damage and initiate DNA repair. The DNA-Damage Binding protein 2 (DDB2) complex is a DRC that initiates nucleotide...

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Main Authors: Dreze, Matija, Calkins, Anne S., Gálicza, Judit, Echelman, Daniel J., Schnorenberg, Mathew R., Fell, Gillian L., Iwai, Shigenori, Fisher, David E., Szüts, David, Iglehart, J. Dirk, Lazaro, Jean-Bernard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904869/
https://ncbi.nlm.nih.gov/pubmed/24489677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085896
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