Structural basis of UV DNA damage recognition by the DDB1-DDB2 complex

UV-light induced pyrimidine photodimers are repaired by the nucleotide excision repair pathway. Photolesions have biophysical parameters closely resembling undamaged DNA, impeding discovery through damage surveillance proteins. The DDB1-DDB2 complex has the highest known affinity for photodimers in...

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Hauptverfasser: Scrima, Andrea, Koníčková, Renata, Czyzewski, Bryan K., Kawasaki, Yusuke, Jeffrey, Philip D., Groisman, Regina, Nakatani, Yoshihiro, Iwai, Shigenori, Pavletich, Nikola P., Thomä, Nicolas H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676164/
https://ncbi.nlm.nih.gov/pubmed/19109893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.10.045
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