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Structural basis of UV DNA damage recognition by the DDB1-DDB2 complex
UV-light induced pyrimidine photodimers are repaired by the nucleotide excision repair pathway. Photolesions have biophysical parameters closely resembling undamaged DNA, impeding discovery through damage surveillance proteins. The DDB1-DDB2 complex has the highest known affinity for photodimers in...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676164/ https://ncbi.nlm.nih.gov/pubmed/19109893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.10.045 |
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