Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors

Numerous molecular effects have been attributed to histone deacetylase inhibitors (HDACI’s), including the induction of major histocompatibility (MHC) genes. Here we report that one FDA approved HDACI, Vorinostat, and a second HDACI currently in clinical trials, Entinostat, reduce the ratio of class...

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Detalhes bibliográficos
Main Authors: Cronin, Kevin, Escobar, Hernando, Szekeres, Karoly, Reyes-Vargas, Eduardo, Rockwood, Alan L., Lloyd, Mark C., Delgado, Julio C., Blanck, George
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903896/
https://ncbi.nlm.nih.gov/pubmed/23328677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23085
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