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Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors

Numerous molecular effects have been attributed to histone deacetylase inhibitors (HDACI’s), including the induction of major histocompatibility (MHC) genes. Here we report that one FDA approved HDACI, Vorinostat, and a second HDACI currently in clinical trials, Entinostat, reduce the ratio of class...

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Bibliografische gegevens
Hoofdauteurs: Cronin, Kevin, Escobar, Hernando, Szekeres, Karoly, Reyes-Vargas, Eduardo, Rockwood, Alan L., Lloyd, Mark C., Delgado, Julio C., Blanck, George
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903896/
https://ncbi.nlm.nih.gov/pubmed/23328677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23085
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