Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors

Numerous molecular effects have been attributed to histone deacetylase inhibitors (HDACI’s), including the induction of major histocompatibility (MHC) genes. Here we report that one FDA approved HDACI, Vorinostat, and a second HDACI currently in clinical trials, Entinostat, reduce the ratio of class...

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Bibliografiske detaljer
Main Authors: Cronin, Kevin, Escobar, Hernando, Szekeres, Karoly, Reyes-Vargas, Eduardo, Rockwood, Alan L., Lloyd, Mark C., Delgado, Julio C., Blanck, George
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903896/
https://ncbi.nlm.nih.gov/pubmed/23328677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23085
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