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Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors

Numerous molecular effects have been attributed to histone deacetylase inhibitors (HDACI’s), including the induction of major histocompatibility (MHC) genes. Here we report that one FDA approved HDACI, Vorinostat, and a second HDACI currently in clinical trials, Entinostat, reduce the ratio of class...

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Autors principals: Cronin, Kevin, Escobar, Hernando, Szekeres, Karoly, Reyes-Vargas, Eduardo, Rockwood, Alan L., Lloyd, Mark C., Delgado, Julio C., Blanck, George
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903896/
https://ncbi.nlm.nih.gov/pubmed/23328677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23085
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