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Humanized telomeres and an attempt to express a functional human telomerase in yeast

The maintenance of telomeric repeat DNA depends on an evolutionarily conserved reverse trans criptase called telomerase. In vitro, only the catalytic subunit and a telomerase-associated RNA are required for the synthesis of species-specific repeat DNA. In an attempt to establish a heterologous syste...

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Detalhes bibliográficos
Main Authors: Bah, Amadou, Bachand, François, Clair, Éveline, Autexier, Chantal, Wellinger, Raymund J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390362/
https://ncbi.nlm.nih.gov/pubmed/15047858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh511
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