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Subtelomeric proteins negatively regulate telomere elongation in budding yeast
The Tbf1 and Reb1 proteins are present in yeast subtelomeric regions. We establish in this work that they inhibit telomerase-dependent lengthening of telomere. For example, tethering the N-terminal domain of Tbf1 and Reb1 in a subtelomeric region shortens that telomere proportionally to the number o...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383556/ https://ncbi.nlm.nih.gov/pubmed/16467854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600975 |
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