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Humanized telomeres and an attempt to express a functional human telomerase in yeast
The maintenance of telomeric repeat DNA depends on an evolutionarily conserved reverse trans criptase called telomerase. In vitro, only the catalytic subunit and a telomerase-associated RNA are required for the synthesis of species-specific repeat DNA. In an attempt to establish a heterologous syste...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390362/ https://ncbi.nlm.nih.gov/pubmed/15047858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh511 |
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