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Telomerase Is Required to Protect Chromosomes with Vertebrate-type T(2)AG(3) 3′ Ends in Saccharomyces cerevisiae

Telomeres containing vertebrate-type DNA repeats can be stably maintained in Saccharomyces cerevisiae cells. We show here that telomerase is required for growth of yeast cells containing these vertebrate-type telomeres. When present at the chromosome termini, these heterologous repeats elicit a DNA...

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Autores principales: Bah, Amadou, Gilson, Eric, Wellinger, Raymund J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149306/
https://ncbi.nlm.nih.gov/pubmed/21676873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.220186
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