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Telomerase Is Required to Protect Chromosomes with Vertebrate-type T(2)AG(3) 3′ Ends in Saccharomyces cerevisiae
Telomeres containing vertebrate-type DNA repeats can be stably maintained in Saccharomyces cerevisiae cells. We show here that telomerase is required for growth of yeast cells containing these vertebrate-type telomeres. When present at the chromosome termini, these heterologous repeats elicit a DNA...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149306/ https://ncbi.nlm.nih.gov/pubmed/21676873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.220186 |
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