Dual Targeting of MEK and PI3K Pathways Attenuates Established and Progressive Pulmonary Fibrosis

Pulmonary fibrosis is often triggered by an epithelial injury resulting in the formation of fibrotic lesions in the lung, which progress to impair gas exchange and ultimately cause death. Recent clinical trials using drugs that target either inflammation or a specific molecule have failed, suggestin...

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Detaylı Bibliyografya
Asıl Yazarlar: Madala, Satish K., Edukulla, Ramakrishna, Phatak, Mukta, Schmidt, Stephanie, Davidson, Cynthia, Acciani, Thomas H., Korfhagen, Thomas R., Medvedovic, Mario, LeCras, Timothy D., Wagner, Kimberly, Hardie, William D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903543/
https://ncbi.nlm.nih.gov/pubmed/24475138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086536
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