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A conformational change in TFIIB is required for activator-mediated assembly of the preinitiation complex
TFIIB plays a pivotal role during assembly of the RNA polymerase II transcription preinitiation complex. TFIIB is composed of two domains that engage in an intramolecular interaction that can be disrupted by the VP16 activation domain. In this study, we describe a novel human TFIIB derivative harbou...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390344/ https://ncbi.nlm.nih.gov/pubmed/15037660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh504 |
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