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The major form of MeCP2 has a novel N-terminus generated by alternative splicing

MeCP2 is a methyl-CpG binding protein that can repress transcription of nearby genes. In humans, mutations in the MECP2 gene are the major cause of Rett syndrome. By searching expressed sequence tag (EST) databases we have found a novel MeCP2 splice isoform (MeCP2α) which encodes a distinct N-termin...

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Bibliografske podrobnosti
Main Authors: Kriaucionis, Skirmantas, Bird, Adrian
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC390342/
https://ncbi.nlm.nih.gov/pubmed/15034150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh349
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