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The major form of MeCP2 has a novel N-terminus generated by alternative splicing
MeCP2 is a methyl-CpG binding protein that can repress transcription of nearby genes. In humans, mutations in the MECP2 gene are the major cause of Rett syndrome. By searching expressed sequence tag (EST) databases we have found a novel MeCP2 splice isoform (MeCP2α) which encodes a distinct N-termin...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390342/ https://ncbi.nlm.nih.gov/pubmed/15034150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh349 |
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