High-frequency structural gene deletion as the basis for functional hemizygosity of the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells.

The CHO-AT3-2 Chinese hamster ovary cell line is functionally hemizygous for the adenine phosphoribosyltransferase (APRT; EC 2.4.2.7) locus. Class 1 APRT +/- heterozygotes, such as CHO-AT3-2, can be isolated at high spontaneous frequencies from wild-type CHO cell populations. Simon et al. [Simon, A....

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Adair, G M, Stallings, R L, Nairn, R S, Siciliano, M J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1983
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.19.5961
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