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DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt; AMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.7) to the aprt+ phenotype by means of DNA-mediated gene transfer. Transformation was effected by using unfractionated...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Wigler, M, Pellicer, A, Silverstein, S, Axel, R, Urlaub, G, Chasin, L
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1979
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383253/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/286319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.3.1373
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