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DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt; AMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.7) to the aprt+ phenotype by means of DNA-mediated gene transfer. Transformation was effected by using unfractionated...

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Detalhes bibliográficos
Main Authors: Wigler, M, Pellicer, A, Silverstein, S, Axel, R, Urlaub, G, Chasin, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383253/
https://ncbi.nlm.nih.gov/pubmed/286319
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