Genetic instability at the adenine phosphoribosyltransferase locus in mouse L cells.

Resistance to adenine analogs such as 2,6-diaminopurine occurs at a rate of approximately 10(-3) per cell per generation in mouse L cells. This resistance is associated with a loss of detectable adenine phosphoribosyltransferase activity. Other genetic loci in L cells have the expected mutation freq...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Tischfield, J A, Trill, J J, Lee, Y I, Coy, K, Taylor, M W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7110133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.3.250-257.1982
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