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Genetic instability at the adenine phosphoribosyltransferase locus in mouse L cells.

Resistance to adenine analogs such as 2,6-diaminopurine occurs at a rate of approximately 10(-3) per cell per generation in mouse L cells. This resistance is associated with a loss of detectable adenine phosphoribosyltransferase activity. Other genetic loci in L cells have the expected mutation freq...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Tischfield, J A, Trill, J J, Lee, Y I, Coy, K, Taylor, M W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1982
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7110133/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.3.250-257.1982
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