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New Nucleophilic Mechanisms of Ros-Dependent Epigenetic Modifications: Comparison of Aging and Cancer

It has been shown that ROS (reactive oxygen species, superoxide and hydrogen peroxide) regulate major epigenetic processes, DNA methylation and histone acetylation, although the mechanism of ROS action (ROS signaling) is still unknown. Both DNA methylation and histone acetylation are nucleophilic pr...

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Bibliografiske detaljer
Hovedforfatter: Afanas’ev, Igor
Format: Artigo
Sprog:Inglês
Udgivet: JKL International LLC 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901614/
https://ncbi.nlm.nih.gov/pubmed/24490117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2014.050052
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