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Reactive oxygen species and age-related genes p66Shc, sirtuin, FoxO3 and klotho in senescence

Reactive oxygen species (ROS) superoxide and hydrogen peroxide perform important signaling functions in many physiological and pathophysiological processes. Cell senescence and organismal age are not exemptions. Aging-regulating genes p66shc, Sirtuin, FOXO3a and Klotho are new important factors whic...

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Autore principale: Afanas'ev, Igor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952092/
https://ncbi.nlm.nih.gov/pubmed/20716932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/oxim.3.2.2
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