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Reactive oxygen species and age-related genes p66Shc, sirtuin, FoxO3 and klotho in senescence

Reactive oxygen species (ROS) superoxide and hydrogen peroxide perform important signaling functions in many physiological and pathophysiological processes. Cell senescence and organismal age are not exemptions. Aging-regulating genes p66shc, Sirtuin, FOXO3a and Klotho are new important factors whic...

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Bibliographic Details
Main Author: Afanas'ev, Igor
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952092/
https://ncbi.nlm.nih.gov/pubmed/20716932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/oxim.3.2.2
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