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New Nucleophilic Mechanisms of Ros-Dependent Epigenetic Modifications: Comparison of Aging and Cancer

It has been shown that ROS (reactive oxygen species, superoxide and hydrogen peroxide) regulate major epigenetic processes, DNA methylation and histone acetylation, although the mechanism of ROS action (ROS signaling) is still unknown. Both DNA methylation and histone acetylation are nucleophilic pr...

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Библиографические подробности
Главный автор: Afanas’ev, Igor
Формат: Artigo
Язык:Inglês
Опубликовано: JKL International LLC 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901614/
https://ncbi.nlm.nih.gov/pubmed/24490117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2014.050052
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