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New Nucleophilic Mechanisms of Ros-Dependent Epigenetic Modifications: Comparison of Aging and Cancer

It has been shown that ROS (reactive oxygen species, superoxide and hydrogen peroxide) regulate major epigenetic processes, DNA methylation and histone acetylation, although the mechanism of ROS action (ROS signaling) is still unknown. Both DNA methylation and histone acetylation are nucleophilic pr...

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Autore principale: Afanas’ev, Igor
Natura: Artigo
Lingua:Inglês
Pubblicazione: JKL International LLC 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901614/
https://ncbi.nlm.nih.gov/pubmed/24490117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2014.050052
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