Llwytho...

Cbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunity

Engagement of the T cell receptor (TCR) with its cognate peptide/MHC initiates a cascade of signaling events that results in T cell activation. Limiting the extent and duration of TCR signaling ensures a tightly constrained response, protecting cells from the deleterious impact of chronic activation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gay, Denise L., Ramón, Hilda, Oliver, Paula M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901516/
https://ncbi.nlm.nih.gov/pubmed/18827983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-008-8034-0
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