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A cycle of ubiquitination regulates adaptor function of the Nedd4-family ubiquitin ligase Rsp5
In yeast, the main ubiquitin ligase responsible for the sorting of proteins to the lysosomal vacuole is Rsp5, a member of the Nedd4 family of ligases whose distinguishing features are a catalytic HECT domain and 3 central WW domains that bind PY motifs in target proteins. Many substrates do not bind...
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| Publicado no: | Curr Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7197006/ https://ncbi.nlm.nih.gov/pubmed/31956026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.11.086 |
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