A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

Immunoglobulin G (IgG) formed during pregnancy against human platelet antigens (HPAs) of the fetus mediates fetal or neonatal alloimmune thrombocytopenia (FNAIT). Because antibody titer or isotype does not strictly correlate with disease severity, we investigated by mass spectrometry variations in t...

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Библиографические подробности
Главные авторы: Kapur, Rick, Kustiawan, Iwan, Vestrheim, Anne, Koeleman, Carolien A. M., Visser, Remco, Einarsdottir, Helga K., Porcelijn, Leendert, Jackson, Dave, Kumpel, Belinda, Deelder, André M., Blank, Dennis, Skogen, Björn, Killie, Mette Kjaer, Michaelsen, Terje E., de Haas, Masja, Rispens, Theo, van der Schoot, C. Ellen, Wuhrer, Manfred, Vidarsson, Gestur
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
Предметы:
Plenary Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901064/
https://ncbi.nlm.nih.gov/pubmed/24243971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-527978
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