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A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy
Immunoglobulin G (IgG) formed during pregnancy against human platelet antigens (HPAs) of the fetus mediates fetal or neonatal alloimmune thrombocytopenia (FNAIT). Because antibody titer or isotype does not strictly correlate with disease severity, we investigated by mass spectrometry variations in t...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901064/ https://ncbi.nlm.nih.gov/pubmed/24243971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-527978 |
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