A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

Immunoglobulin G (IgG) formed during pregnancy against human platelet antigens (HPAs) of the fetus mediates fetal or neonatal alloimmune thrombocytopenia (FNAIT). Because antibody titer or isotype does not strictly correlate with disease severity, we investigated by mass spectrometry variations in t...

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Hlavní autoři: Kapur, Rick, Kustiawan, Iwan, Vestrheim, Anne, Koeleman, Carolien A. M., Visser, Remco, Einarsdottir, Helga K., Porcelijn, Leendert, Jackson, Dave, Kumpel, Belinda, Deelder, André M., Blank, Dennis, Skogen, Björn, Killie, Mette Kjaer, Michaelsen, Terje E., de Haas, Masja, Rispens, Theo, van der Schoot, C. Ellen, Wuhrer, Manfred, Vidarsson, Gestur
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
Plenary Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901064/
https://ncbi.nlm.nih.gov/pubmed/24243971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-527978
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